My
PrREXULTI®
Every journey begins with a single step
Why REXULTI?
You have been prescribed REXULTI, along with an antidepressant, because:
- You were diagnosed with major depressive disorder (MDD); and
- You had an inadequate response to your antidepressant, meaning not all your symptoms have been resolved.
How does REXULTI work?
Your brain uses naturally occurring chemicals – called neurotransmitters – to allow nerve cells to talk to each other.
When you have depression, certain neurotransmitters may be out of balance. These imbalances may cause some of the symptoms you have experienced.
REXULTI, used together with an antidepressant, can affect these neurotransmitters and help you manage your depression symptoms.
Exactly how REXULTI works is unknown, but it seems that REXULTI corrects the balance of certain neurotransmitters like dopamine and serotonin in your body.
REXULTI is indicated for use as an adjunct to antidepressants for the treatment of major depressive disorder (MDD) in adult patients with an inadequate response to prior antidepressant treatments during the current episode.
How do I take REXULTI?
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The usual starting dose is 0.5 mg or 1 mg once a day
The recommended target and maximum dose is 2 mg once a day
REXULTI can be taken with or without food.
Take REXULTI exactly as your healthcare professional tells you to take it.
- Your healthcare professional has decided on the best dosage for you depending on your overall health and other medications you are taking.
- Your healthcare professional may change your dose depending on how you respond.
- Do not change your dose or stop taking REXULTI without speaking to your healthcare professional.
Missed dose
- You should not miss a dose of REXULTI. If you miss a dose, take the missed dose as soon as you remember.
- If you are close to your next dose, just skip the missed dose and take your next dose at your regular time.
- Do not take 2 doses of REXULTI at the same time.
- If you are not sure about your dosing, call your healthcare professional.
Overdose
- If you think you have taken too much REXULTI, contact your healthcare professional, hospital emergency department or regional Poison Control Centre immediately, even if there are no symptoms.
What are the warnings and precautions with REXULTI?
Serious warnings and precautions
Medicines like REXULTI, called atypical antipsychotics, can raise the risk of death in elderly people who have dementia. REXULTI is not to be used in patients with dementia.
Possible side effects include:
- Diarrhea, constipation
- Indigestion, stomach pain
- Dry mouth
- Weight gain, increased appetite
- Dizziness
- Difficulty staying still or restlessness
- Shakiness (tremor)
- Back pain, muscle pain
- Sleepiness, drowsiness, fatigue, weakness, sleep disturbances (insomnia)
- Anxiety
- Headache
- Nasopharyngitis (common cold-like symptoms)
- Rash
- Sleep apnea (a sleep disorder where your breathing is interrupted during sleep)
- Sleepwalking and eating while asleep (sleep related eating disorders)
These are not all the possible side effects you may feel when taking REXULTI. If you experience any side effects not listed here, contact your healthcare professional.
Although uncommon, serious side effects are possible. Consult your healthcare professional to learn about them.
Refer to REXULTI’s patient medication information for complete information about other warnings regarding thoughts of suicide and worsening of depression or other mental illnesses, impulse behaviours, effects in newborns, falls, serious allergic reactions, neuroleptic malignant syndrome, high levels of prolactin, driving and using machines, low blood pressure, dehydrating and overheating, blood tests, and medicines that may interact with REXULTI.